Serum ferritin and hematological indices in thalassemia minor and nontransfusion dependent hemoghlobinopathy
نویسندگان
چکیده
منابع مشابه
Relationship between serum ferritin and growth status of pediatric transfusion dependent thalassemia
Background: Growth retardation is a long-term complication in pediatric transfusion-dependent thalassemias (TDTs), presented as short-stature and upper body segment shortening. The cause of this condition was chronic hypoxia, iron overload, endocrinopathy, inadequate transfusion, and iron chelation. We analyze the relationship between ferritin level and growth status of pediatric TDTs. Methods...
متن کاملNovel Approach to Reactive Oxygen Species in Nontransfusion-Dependent Thalassemia
The term Nontransfusion dependent thalassaemia (NTDT) was suggested to describe patients who had clinical manifestations that are too severe to be termed minor yet too mild to be termed major. Those patients are not entirely dependent on transfusions for survival. If left untreated, three main factors are responsible for the clinical sequelae of NTDT: ineffective erythropoiesis, chronic hemolyt...
متن کاملThe relation between left ventricular diastolic indices and serum ferritin in thalassemia major.
Iron-induced heart failure is the primary cause of death in thalassemia major patients who receive continuous transfusions. Recent studies have suggested that diastolic function is impaired prior to systolic function in process of hemochromatosis, but they did not come to agreement on the first impaired diastolic index. Additionally, serum ferritin concentration is not a reliable indicator of b...
متن کاملEvaluation of the Relationship between Serum Ferritin Level and Renal Function in Patients with Thalassemia Major
Background and Aim: Serum ferritin in patients with thalassemia major is an indicator of iron overload, which is the main cause of damage to various organs of the body in patients with thalassemia major. The aim of this study was to investigate the relationship between serum ferritin level and renal function in thalassemia major patients. Materials and Methods: This descriptive and cross-sectio...
متن کاملEfficacy of Chicory in Decreasing Serum Ferritin and Liver Enzymes in Major Beta Thalassemia Patients
Abstract Objective Thalassemia major is a severe transfusion-dependent anemia that needs iron chalation therapy to remove iron overload. The objectives of the present study were to assess the iron overload liver response to inulin of chicory supplementation by evaluating the serum ferritin and liver enzymes. Methods Among 70 beta thalassemia patients, 50 were selected for chelating therapy ...
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ژورنال
عنوان ژورنال: Iraqi Journal of Hematology
سال: 2021
ISSN: 2072-8069
DOI: 10.4103/ijh.ijh_18_20